Chlamydia trachomatis-associated tubal factor subfertility: immunogenetic aspects and serological screening
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چکیده
منابع مشابه
Chlamydia trachomatis-associated tubal factor subfertility: Immunogenetic aspects and serological screening.
Chlamydia (C.) trachomatis female genital tract infections usually remain asymptomatic and untreated. Therefore, an adequate immune response, rather than antibiotic treatment, is essential to clear the pathogen. Most women will effectively clear C. trachomatis infections, but some will have persistent C. trachomatis infections, which may ascend to the upper genital tract and increase the risk o...
متن کاملImmunogenetic correlates for Chlamydia trachomatis-associated tubal infertility.
OBJECTIVE To understand immunogenetic mechanisms of Chlamydia trachomatis infection and tubal scarring. METHODS We measured and compared previously significant human leukocyte antigen (HLA) class II DQ alleles, their linked DRB genes, and polymorphisms in selected cytokine genes (tumor necrosis factor alpha-308 promoter; transforming growth factor beta1-10 and -25 codons; interleukin 10-1082,...
متن کاملScreening strategies for tubal factor subfertility.
BACKGROUND Different screening strategies exist to estimate the risk of tubal factor subfertility, preceding laparoscopy. Three screening strategies, comprising Chlamydia trachomatis IgG antibody testing (CAT), high-sensitivity C-reactive protein (hs-CRP) testing and hysterosalpingography (HSG), were explored using laparoscopy as reference standard and the occurrence of a spontaneous pregnancy ...
متن کاملScreening strategies for tubal factor subfertility
J.E. den Hartog1,5, C.M.J.G. Lardenoije1, J.L. Severens2,3, J.A. Land1,4, J.L.H. Evers1 and A.G.H. Kessels2 Research Institute Growth and Development (GROW), Department of Obstetrics and Gynaecology, Maastricht University Medical Centre, PO Box 5800, 6202 AZ Maastricht, The Netherlands; Department of Clinical Epidemiology and Medical Technology Assessment (KEMTA), Maastricht University Medical ...
متن کاملCan screening Chlamydia trachomatis by serological tests predict tubal damage in infertile patients?
Effectiveness of screening Chlamydia trachomatis (CT) antibody to predict tubal damage was assessed in this prospective study which was performed in a teaching hospital between September 2003 and September 2004. The study group consisted of 152 patients who underwent laparoscopy for infertility and the control group consisted of 80 fertile women who gave birth in the same hospital. CT antibody ...
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ژورنال
عنوان ژورنال: Human Reproduction Update
سال: 2006
ISSN: 1460-2369,1355-4786
DOI: 10.1093/humupd/dml030